'Artificial Pancreas' Approved for Type 1 Diabetes

Title: 'Artificial Pancreas' Approved for Type 1 Diabetes
Category: Health News
Created: 9/28/2016 12:00:00 AM
Last Editorial Review: 9/29/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cPBZcJ

Trulicity (dulaglutide)

Title: Trulicity (dulaglutide)
Category: Medications
Created: 9/28/2016 12:00:00 AM
Last Editorial Review: 9/28/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2dr4vPo

25 Legends: Laura Nolan

This year marks the 25th anniversary of two American Diabetes Association® signature fundraising events—Step Out Walk to Stop Diabetes® and Tour de Cure®.

Every dollar raised at these events supports people living with diabetes and funds our life-changing research and programs.

The “25 Legends” blog series highlights personal stories from some of the Association’s most dedicated walkers and riders who are affected by the disease.

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Summer 1973: I had just finished the eighth grade. I was a little nervous but very excited at the prospect of starting high school and a new chapter in my life.  But little did I know just how much my life was going to change over the next few months.

Ever since I was a young adult, I have always spent a great deal of time outdoors. I especially loved going on walks and bike rides with my dad because they felt like a fun adventure. Suddenly, however, they became a different kind of adventure—as we needed to search for places to stop so I could quench my ever-increasing thirst and go to the bathroom.

My life at home was also changing for the worse. It seemed like all I did was drink ice water, run to the bathroom and sit around completing crossword puzzles. I quickly lost weight and ran out of energy. When my parents finally called my pediatrician on June 26, he thought the symptoms were related to my asthma. But later that day, I slipped into a coma.

I remember hearing the emergency room doctors tell my parents that I might die—my blood glucose was 1,500 and I was extremely sick. I wanted so badly to tell my parents that I could hear them and I would be okay, but I could not speak. When I awoke from the coma the next morning, I found out that I had type 1 diabetes. I was told I would have this disease the rest of my life. I would have to take insulin injections because my body could no longer produce insulin. I was terrified.

Five years later, I began nursing school and was still relatively unfamiliar with diabetes, despite having lived with it for a while. The program taught me not only how to help others with the disease, but also how to improve my own diabetes management. In March 1980, I started using an insulin pump and, within three weeks, I found my passion in helping others begin pump therapy. Since finishing nursing school and becoming a certified diabetes educator, I have placed thousands of patients on insulin pumps and continuous glucose monitors. Watching the technology improve their lives, like it did mine, was amazing. 

Over the course of my life, I have worked for multiple hospitals and for Medtronic Diabetes, and I’ve owned my own business—ABC Diabetes Consultants—which offers diabetes education programs. I have also volunteered extensively with the American Diabetes Association Phoenix office.

Laura, center, with Pump Squad walkers Joan and Grace.

I discovered Step Out Walk to Stop Diabetes in 1991 and immediately reached out to my family, friends and colleagues to create a team. We originally called ourselves the Valley Insulin Pumpers, followed by Control Diabetes and Wacky Walkers. In 2001, however, my daughter (who was 12 years old at the time) proposed Pump Squad in honor of my insulin pump and those of my patients walking with us. Pump Squad has remained the team name for the past 15 years.

Pump Squad has been recognized as a Top 10 Fundraiser multiple times in my region. Last year, we raised over $9,000. In addition, three of us were Champion fundraisers—raising over $1,000 each. I am very grateful for my family, friends and patients for coming out to the walk each year.

Participating in the walks inspired me to join my local office’s Speakers Bureau, Diabetes EXPO Volunteer Committee and Step Out Planning Committee—all while working as a nurse and diabetes educator. Finally, I volunteered at Camp AZDA in Prescott, Ariz., for eight years. Watching children and young adults adjust to life with diabetes and support one another is a truly rewarding experience.

Although diabetes is difficult to live with, it has made me a better, stronger person. If it were not for diabetes, I may not have pursued a career in nursing or diabetes education—or found a supportive community. Each year, watching my Pump Squad walk to help others affected by diabetes makes me so proud. My daughter, who is now 27 years old, recently reminded me that I used to take her in a stroller during the first several walks. Neither of us can believe we have participated for 24 years. As I write out my donations request letter for the 25^th time, I am more motivated than ever to help others with diabetes and to find a cure.

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Together, we CAN Stop Diabetes.

The Association is so grateful for our 25 Legends! Their tireless efforts as walkers and riders are a tremendous support and inspiration to people with diabetes.

Sign up today! Learn more about these events and find out how to get involved at diabetes.org/stepout and http://ift.tt/1qKFQGM.

Source Diabetes Stops Here http://ift.tt/2d9O8MA

#IDriveMyHealth: Lisa’s Story

Nearly three in four NASCAR^® fans are impacted by diabetes, which affects approximately 30 million people nationwide. The Drive to Stop Diabetes^SM campaign, presented by Lilly Diabetes in collaboration with the American Diabetes Association^®, strives to empower Americans with diabetes to live well. The face of the campaign, NASCAR XFINITY Series driver Ryan Reed, has type 1 diabetes and is an inspiration for all people with the disease.

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As we have all realized at one point or another, life is full of surprises. Type 1 diabetes was definitely not one of the better surprises I received. Despite being born 20 years ago, I feel like my story really began in August 2007 when I was diagnosed with diabetes.

Although I always try to make lemonade out of lemons, adjusting to life with diabetes was not easy. Since I was only 11 years old when I was diagnosed, I could not fully comprehend the disease and did not realize how much of an impact it would have on my life.

Diabetes management is a lot to learn—you constantly need to remember things that never used to matter (i.e., counting carbohydrates, taking insulin, checking your blood glucose multiple times every day, maintaining a fitness routine). However, being the adaptable person I am, I believe I dealt with the change quite well. With my family’s support, I accepted that I did not have a choice—this was the way my life had to be.

Nine years later, diabetes has come to be a part of me just like my hair, nose or anything else. It’s just there. I am not limited by it. Anything I want to do in a given moment is up to me—I just have to keep my blood glucose in mind. The only moments I consciously think about diabetes are when, once in a while, someone asks me about the machine that’s in my pocket or the odd cable that’s attached to me. And, with a smile, I educate the person about my situation and at the same time raise awareness about diabetes.

I am an athlete. I show jump on international arenas—and diabetes does not distract me from my goals. I dedicate at least four hours every day to horseback riding. As a rider, it is my duty to train and prepare my three young horses for any challenges we might face in competition. My discipline and passion, stemming partly from diabetes and partly from caring for my horses, have had a significant influence on my approach to the sport.

Although I have diabetes, it is not the most significant thing about me. So, I suppose now would be a good time to start over and formally introduce myself. My name is Lisa, and I am 20 years old. I was born in New Jersey but currently live in Warsaw, Poland—my family was born there and I compete in show jumping championships such as the World Cup Qualifier for the Central European League. When I am not riding my horses, I spend each day in this beautiful city studying or socializing at my university. I have a Facebook page that I use to inspire others to pursue their ambitions despite diseases such as diabetes. I encourage them to embrace and accept their challenges, whatever they may be.

I support Ryan Reed and the Drive to Stop Diabetes campaign because it motivates people to continue enjoying life, even when diabetes is along for the ride. The moment people lose sight of that, the disease wins. Ryan Reed is an inspiration, and just as he encourages his fans to stay active and healthy with diabetes, my #IDriveMyHealth message is to know that diabetes is just a part of you. It doesn’t have to define you.

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Are you a NASCAR fan impacted by diabetes? Share your healthy lifestyle tips with us on social media, using #IDriveMyHealth.

To learn more about the Drive to Stop Diabetes campaign and find out how to get involved, visit http://ift.tt/1Orwomd.

Source Diabetes Stops Here http://ift.tt/2damMBO

Combined ultrasound and electric field stimulation prompts an immediate response in stalled chronic wounds

Source Chronic Wound Care Management and Research http://ift.tt/2d3NwVz

Live. Work. Play: Eric’s Diabetes Story

Working for the American Diabetes Association^® means making a difference for millions of people and working toward a future free of diabetes and all its burdens.

We all have a story to share. Some of us live with type 1 or type 2 diabetes, gestational diabetes or prediabetes. Others have loved ones with the disease or have lost someone to the fight.

The following are personal stories from the Association’s staff about why we are so committed to the mission to prevent and cure diabetes and to improve the lives of all people affected by diabetes.

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Eric Cortes
Senior Manager, Social Media & Digital Engagement
Home Office (Alexandria, Va.)

I’m almost two times more likely to be diagnosed with diabetes. Why? Because I’m Latino.

When I started working with the American Diabetes Association in July 2015, this statistic became forever etched in my memory: Compared with non-Hispanic whites, the risk of being diagnosed with diabetes is 1.7 times higher among Latinos/Hispanics. Did it make me think twice about my eating habits and exercise regimen? It most certainly did. It also made me think about my family history.

I remember that after learning about my career move, my father mentioned that my mother was on the brink of developing prediabetes. She wasn’t diagnosed yet, but her doctors recommended she watch her eating habits and start moving more. This news made my father push her to exercise more often. “Go out for a walk during lunch,” he regularly tells her.

My grandmother was living with type 2 diabetes, but she recently passed away. I didn’t want my mom to face a similar type 2 diagnosis and its complications. When I visit my parents, I push my mom to take a walk and avoid those pesky eating habits we grew up with—and sometimes maintain today. When I was growing up, our family would constantly eat at fast-food restaurants.

In addition, after I told my brother and his wife I was moving to Virginia for the job, my sister-in-law mentioned her very close friend, Claire, who is living with type 1 diabetes. You may remember her from a recent Diabetes Stops Here blog post written by her mother, Marcie. Since meeting Claire, I’ve learned more about her, including how she manages her diabetes and the awesome fact that she’s been participating in Tour de Cure^® for many years!

Team Moxie from left: Eric , Marcie and Claire.

Claire spoke to me about her involvement with the Association’s local D.C. office and then asked if I wanted to join Team Moxie, the top Tour de Cure Family and Friends team in the local area. I gladly accepted the invitation to the event, which took place in June. It was going to be my first long ride—a challenging 36 miles—but I knew it would benefit my health in addition to raising funds for the Association. The ride was also a great opportunity to work with the local office and Claire to record a Facebook Live during her ride. (Go Red Rider! You can watch the recorded stream on our Tour de Cure Facebook page.)

And thank God for rest stops! I’m in no way an avid cyclist. I was happy to take quick breaks along the course. The raisins and energy drinks provided by volunteers boosted my will to keep going and finish. After completing the ride in about three and a half hours, I felt wonderful. In fact, the feeling was so good that I continued to ride my bicycle. I ride twice a week to and from work—4 miles each way—for a total of 16 miles a week. This is also helping me train for an upcoming 50-mile Tour de Cure!

So why did I become involved with the American Diabetes Association? It was an opportunity to make a difference in the lives of all people with diabetes. In the past year, I’ve learned so much that has helped not only with my own health, but also with the health of my family and friends. Working in social media also provides an opportunity to speak with people across the country and hear their stories. I’ve worked on many projects and campaigns that benefit the diabetes community. The disease can be scary, but I smile anytime I read or listen to a story on perseverance and overcoming the many obstacles diabetes throws at you.

It’s disheartening to read that 12.8 percent of the Latino/Hispanic population in the United States lives with diabetes. However, I’m happy to know that everything I work on—from a short tweet to an extensive Facebook Live video—makes a difference.

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To learn more about nationwide employment opportunities and life at the Association, please visit diabetes.org/careers.

Source Diabetes Stops Here http://ift.tt/2dp6rgu

tolazamide (Tolinase brand has been discontinued.)

Title: tolazamide (Tolinase brand has been discontinued.)
Category: Medications
Created: 3/2/2005 12:00:00 AM
Last Editorial Review: 9/23/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cTNYbT

Avandamet (rosiglitazone/metformin)

Title: Avandamet (rosiglitazone/metformin)
Category: Medications
Created: 3/2/2005 12:00:00 AM
Last Editorial Review: 9/21/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2dh216M

Actos (pioglitazone)

Title: Actos (pioglitazone)
Category: Medications
Created: 11/28/1999 12:00:00 AM
Last Editorial Review: 9/20/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cTOxlY

Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling

Type 1 diabetes (T1D) negatively influences skeletal muscle health; however, its effect on muscle satellite cells (SCs) remains largely unknown. SCs from samples from rodents (Akita) and human subjects with T1D were examined to discern differences in SC density and functionality compared with samples from their respective control subjects. Examination of the Notch pathway was undertaken to investigate its role in changes to SC functionality. Compared with controls, Akita mice demonstrated increased muscle damage after eccentric exercise along with a decline in SC density and myogenic capacity. Quantification of components of the Notch signaling pathway revealed a persistent activation of Notch signaling in Akita SCs, which could be reversed with the Notch inhibitor DAPT. Similar to Akita samples, skeletal muscle from human subjects with T1D displayed a significant reduction in SC content, and the Notch ligand, DLL1, was significantly increased compared with control subjects, supporting the dysregulated Notch pathway observed in Akita muscles. These data indicate that persistent activation in Notch signaling impairs SC functionality in the T1D muscle, resulting in a decline in SC content. Given the vital role played by the SC in muscle growth and maintenance, these findings suggest that impairments in SC capacities play a primary role in the skeletal muscle myopathy that characterizes T1D.

Source Diabetes Pathophysiology http://ift.tt/2cVbGk0

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

Activation of the p53 pathway in adipose tissue contributes to insulin resistance associated with obesity. However, the mechanisms of p53 activation and the effect on adipocyte functions are still elusive. Here we found a higher level of DNA oxidation and a reduction in telomere length in adipose tissue of mice fed a high-fat diet and an increase in DNA damage and activation of the p53 pathway in adipocytes. Interestingly, hallmarks of chronic DNA damage are visible at the onset of obesity. Furthermore, injection of lean mice with doxorubicin, a DNA damage-inducing drug, increased the expression of chemokines in adipose tissue and promoted its infiltration by proinflammatory macrophages and neutrophils together with adipocyte insulin resistance. In vitro, DNA damage in adipocytes increased the expression of chemokines and triggered the production of chemotactic factors for macrophages and neutrophils. Insulin signaling and effect on glucose uptake and Glut4 translocation were decreased, and lipolysis was increased. These events were prevented by p53 inhibition, whereas its activation by nutlin-3 reproduced the DNA damage-induced adverse effects. This study reveals that DNA damage in obese adipocytes could trigger p53-dependent signals involved in alteration of adipocyte metabolism and secretory function leading to adipose tissue inflammation, adipocyte dysfunction, and insulin resistance.

Source Diabetes Pathophysiology http://ift.tt/2dndiFX

Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase

MicroRNAs (miRNAs) have a fundamental role in diabetic heart failure. The cardioprotective miRNA-133a (miR-133a) is downregulated, and contractility is decreased in diabetic hearts. Norepinephrine (NE) is a key catecholamine that stimulates contractility by activating β-adrenergic receptors (β-AR). NE is synthesized from tyrosine by the rate-limiting enzyme, tyrosine hydroxylase (TH), and tyrosine is catabolized by tyrosine aminotransferase (TAT). However, the cross talk/link between TAT and TH in the heart is unclear. To determine whether miR-133a plays a role in the cross talk between TH and TAT and regulates contractility by influencing NE biosynthesis and/or β-AR levels in diabetic hearts, Sprague-Dawley rats and miR-133a transgenic (miR-133aTg) mice were injected with streptozotocin to induce diabetes. The diabetic rats were then treated with miR-133a mimic or scrambled miRNA. Our results revealed that miR-133a mimic treatment improved the contractility of the diabetic rat’s heart concomitant with upregulation of TH, cardiac NE, β-AR, and downregulation of TAT and plasma levels of NE. In miR-133aTg mice, cardiac-specific miR-133a overexpression prevented upregulation of TAT and suppression of TH in the heart after streptozotocin was administered. Moreover, miR-133a overexpression in CATH.a neuronal cells suppressed TAT with concomitant upregulation of TH, whereas knockdown and overexpression of TAT demonstrated that TAT inhibited TH. Luciferase reporter assay confirmed that miR-133a targets TAT. In conclusion, miR-133a controls the contractility of diabetic hearts by targeting TAT, regulating NE biosynthesis, and consequently, β-AR and cardiac function.

Source Diabetes Pathophysiology http://ift.tt/2cVdhGq

High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I

Disordered neovascularization and impaired wound healing are important contributors to diabetic vascular complications. We recently showed that high-density lipoproteins (HDLs) enhance ischemia-mediated neovascularization, and mounting evidence suggests HDL have antidiabetic properties. We therefore hypothesized that HDL rescue diabetes-impaired neovascularization. Streptozotocin-induced diabetic mice had reduced blood flow recovery and neovessel formation in a hindlimb ischemia model compared with nondiabetic mice. Reconstituted HDL (rHDL) infusions in diabetic mice restored blood flow recovery and capillary density to nondiabetic levels. Topical rHDL application rescued diabetes-impaired wound closure, wound angiogenesis, and capillary density. In vitro, rHDL increased key mediators involved in hypoxia-inducible factor-1α (HIF-1α) stabilization, including the phosphoinositide 3-kinase/Akt pathway, Siah1, and Siah2, and suppressed the prolyl hydroxylases (PHD) 2 and PHD3. rHDL rescued high glucose–induced impairment of tubulogenesis and vascular endothelial growth factor (VEGF) A protein production, a finding associated with enhanced phosphorylation of proangiogenic mediators VEGF receptor 2 and endothelial nitric oxide synthase. Siah1/2 small interfering RNA knockdown confirmed the importance of HIF-1α stability in mediating rHDL action. Lentiviral short hairpin RNA knockdown of scavenger receptor class B type I (SR-BI) in vitro and SR-BI^–/– diabetic mice in vivo attenuated rHDL rescue of diabetes-impaired angiogenesis, indicating a key role for SR-BI. These findings provide a greater understanding of the vascular biological effects of HDL, with potential therapeutic implications for diabetic vascular complications.

Source Diabetes Pathophysiology http://ift.tt/2dnc3H1

Expression of Interferon-Stimulated Genes in Insulitic Pancreatic Islets of Patients Recently Diagnosed With Type 1 Diabetes

A primary insult to the pancreatic islets of Langerhans, leading to the activation of innate immunity, has been suggested as an important step in the inflammatory process in type 1 diabetes (T1D). The aim of this study was to examine whether interferon (IFN)-stimulated genes (ISGs) are overexpressed in human T1D islets affected with insulitis. By using laser capture microdissection and a quantitative PCR array, 23 of 84 examined ISGs were found to be overexpressed by at least fivefold in insulitic islets from living patients with recent-onset T1D, participating in the Diabetes Virus Detection (DiViD) study, compared with islets from organ donors without diabetes. Most of the overexpressed ISGs, including GBP1, TLR3, OAS1, EIF2AK2, HLA-E, IFI6, and STAT1, showed higher expression in the islet core compared with the peri-islet area containing the surrounding immune cells. In contrast, the T-cell attractant chemokine CXCL10 showed an almost 10-fold higher expression in the peri-islet area than in the islet, possibly partly explaining the localization of T cells mainly to this region. In conclusion, insulitic islets from recent-onset T1D subjects show overexpression of ISGs, with an expression pattern similar to that seen in islets infected with virus or exposed to IFN-/interleukin-1β or IFN-α.

Source Diabetes Pathophysiology http://ift.tt/2cVbdyo

Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice

Decreased heat shock protein (Hsp) expression in type 1 and type 2 diabetes has been implicated as a primary factor contributing to diabetes-induced organ damage. We recently showed that diabetic cardiomyocytes could release detrimental exosomes, which contain lower levels of Hsp20 than normal ones. To investigate whether such detrimental exosomes could be modified in cardiomyocytes by raising Hsp20 levels to become protective, we used a transgenic (TG) mouse model with cardiac-specific overexpression of Hsp20. TG and control wild-type (WT) mice were injected with streptozotocin (STZ) to induce diabetes. We observed that overexpression of Hsp20 significantly attenuated STZ-caused cardiac dysfunction, hypertrophy, apoptosis, fibrosis, and microvascular rarefaction. Moreover, Hsp20-TG cardiomyocytes exhibited an increased generation/secretion of exosomes by direct interaction of Hsp20 with Tsg101. Of importance, exosomes derived from TG cardiomyocytes encased higher levels of Hsp20, p-Akt, survivin, and SOD1 than WT exosomes and protected against in vitro hyperglycemia-triggered cell death, as well as in vivo STZ-induced cardiac adverse remodeling. Last, blockade of exosome generation by GW4869 remarkably offset Hsp20-mediated cardioprotection in diabetic mice. Our results indicate that elevation of Hsp20 in cardiomyocytes can offer protection in diabetic hearts through the release of instrumental exosomes. Thus, Hsp20-engineered exosomes might be a novel therapeutic agent for diabetic cardiomyopathy.

Source Diabetes Pathophysiology http://ift.tt/2d0oVhQ

Canada's First Nations People Face Greater Diabetes Risk

Title: Canada's First Nations People Face Greater Diabetes Risk
Category: Health News
Created: 9/19/2016 12:00:00 AM
Last Editorial Review: 9/20/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cT4Zh0

Marriage May Help Diabetics Keep Weight Off

Title: Marriage May Help Diabetics Keep Weight Off
Category: Health News
Created: 9/16/2016 12:00:00 AM
Last Editorial Review: 9/19/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cztzDu

A prospective case series evaluating the safety and efficacy of the Klox BioPhotonic System in venous leg ulcers

Source Chronic Wound Care Management and Research http://ift.tt/2cjIdTE

Amaryl (glimepiride)

Title: Amaryl (glimepiride)
Category: Medications
Created: 4/3/1999 12:00:00 AM
Last Editorial Review: 9/16/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cE88nH

Could Fish Oil Fatty Acids Raise a Woman's Risk for Diabetes?

Title: Could Fish Oil Fatty Acids Raise a Woman's Risk for Diabetes?
Category: Health News
Created: 9/16/2016 12:00:00 AM
Last Editorial Review: 9/16/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2d56PMK

Study Sees Link Between Long Naps, Type 2 Diabetes Risk

Title: Study Sees Link Between Long Naps, Type 2 Diabetes Risk
Category: Health News
Created: 9/14/2016 12:00:00 AM
Last Editorial Review: 9/15/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2crm7dS

Tradjenta (linagliptin)

Title: Tradjenta (linagliptin)
Category: Medications
Created: 5/3/2011 12:00:00 AM
Last Editorial Review: 9/14/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2csNWV8

Victoza (liraglutide)

Title: Victoza (liraglutide)
Category: Medications
Created: 2/17/2012 12:00:00 AM
Last Editorial Review: 9/14/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2coOK0h

Is Summer Peak Time for Diabetes Tied to Pregnancy?

Title: Is Summer Peak Time for Diabetes Tied to Pregnancy?
Category: Health News
Created: 9/13/2016 12:00:00 AM
Last Editorial Review: 9/14/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2csOlqL

Bodybuilders' Steroid Abuse Linked to Pre-Diabetic Condition

Title: Bodybuilders' Steroid Abuse Linked to Pre-Diabetic Condition
Category: Health News
Created: 9/14/2016 12:00:00 AM
Last Editorial Review: 9/14/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2coP7Iw

25 Legends: Cristie Field

This year marks the 25th anniversary of two American Diabetes Association® signature fundraising events—Step Out Walk to Stop Diabetes® and Tour de Cure®.

Every dollar raised at these events supports people living with diabetes and funds our life-changing research and programs.

The “25 Legends” blog series highlights personal stories from some of the Association’s most dedicated walkers and riders who are affected by the disease.

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When I cycled in my first Tour de Cure five years ago, I had no idea that it would become one of my biggest passions and an event I look forward to every year.

Cristie Field, pictured right, with husband Joshua Field.

My name is Cristie Field. I am 35 years old and currently live in Chicago. My husband and I began participating in the Chicagoland Tour de Cure five years after I was diagnosed with type 2 diabetes.

The diagnosis came as a huge surprise and completely changed my life—I was only 25 and had recently graduated college. I always lived a reasonably healthy lifestyle and was a ballet dancer for many years. However, the summer after college, my weight fluctuated and I felt constantly exhausted. I just did not feel like myself.

It was Bell’s palsy that finally landed me in the hospital in August of that year—but the doctor seemed more concerned about something else. I vividly remember him asking if diabetes ran in my family, and me telling him to calm down when he mentioned my blood glucose was high. After all, I had just consumed a small Frappuccino® and part of a Rice Krispies® treat. Little did I know that my blood glucose was nearly 600mg/dL and my A1c was 12.6. Needless to say, I had diabetes.

From that moment on, I was forced to constantly count carbohydrates, poke myself with needles and worry about potential complications. I was terrified. However, I channeled those feelings into an effort to get as healthy as I could–and I did! The support I received from my family and friends is more than I could ever ask for. They are patient when I’m “hangry” and always make sure there is something for me to eat in case my blood glucose goes low. More notably, they have supported my small, but mighty, Tour de Cure team, the A1Cyclists, for the past four years.

My initial Tour de Cure left me feeling nothing short of inspired. I became committed to raising funds for research and children’s camps, as well as advocating for all of us in the diabetes community. Each year, my family and friends raise at least $3,000, and my mother and I are proud to be Champion Tour de Cure fundraisers. Not only do I ride for those living with diabetes, but I also ride for my family members and friends who are affected by it daily.

At the Tour this past June, my appreciation for my support system amplified. I was unable to ride because I was 17 weeks pregnant at the time, so I spent the day volunteering in the American Diabetes Association’s Red Rider tent. I cheered on cyclists and provided them with snacks, cooling wraps and all the moral support they could need. I also participated on the local Red Rider Planning Committee this year, raising awareness and helping newly diagnosed individuals. This role enabled me to give back to an organization that gives so much hope and support to those with diabetes.

Being pregnant with diabetes is no easy feat. In fact, the disease held me back from becoming a mother for years. However, with the amazing support of my family and friends, my OB-GYN and my maternal- fetal medicine team, I know I am in good hands and a healthy pregnancy is possible. I closely monitor my blood glucose, visit the doctor every other week and do not give in to late-night ice cream cravings. It is definitely a challenge, but I know that my health—and my growing baby boy’s health—is well worth it.

In 2017, I look forward to rejoining fellow Red Riders on the cycling trail, as well as continuing my involvement on the Red Rider Planning Committee. And I cannot wait to bring my son (due in November) to his first Tour de Cure next year!

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Together, we CAN Stop Diabetes.

The Association is so grateful for our 25 Legends! Their tireless efforts as walkers and riders are a tremendous support and inspiration to people with diabetes.

Sign up today! Learn more about these events and find out how to get involved at diabetes.org/stepout and http://ift.tt/1qKFQGM.

Source Diabetes Stops Here http://ift.tt/2cncm5J

Many With Diabetes Missing Out on Statins

Title: Many With Diabetes Missing Out on Statins
Category: Health News
Created: 9/12/2016 12:00:00 AM
Last Editorial Review: 9/13/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cUsyuQ

Diabetes During Pregnancy Could Pose Harm to Baby

Title: Diabetes During Pregnancy Could Pose Harm to Baby
Category: Health News
Created: 9/13/2016 12:00:00 AM
Last Editorial Review: 9/13/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cml3Ih

Pilots on Insulin Therapy Can Safely Fly Commercial Planes: Study

Title: Pilots on Insulin Therapy Can Safely Fly Commercial Planes: Study
Category: Health News
Created: 9/13/2016 12:00:00 AM
Last Editorial Review: 9/13/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cUt6kE

Adlyxin (lixisenatide)

Title: Adlyxin (lixisenatide)
Category: Medications
Created: 9/13/2016 12:00:00 AM
Last Editorial Review: 9/13/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cmkzBO

Type 1 Diabetes

Title: Type 1 Diabetes
Category: Diseases and Conditions
Created: 1/31/2005 12:00:00 AM
Last Editorial Review: 9/12/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2crJaVm

metformin, Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet

Title: metformin, Glucophage, Glucophage XR, Glumetza, Fortamet, Riomet
Category: Medications
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 9/9/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2ctKAnk

Type 2 Diabetes

Title: Type 2 Diabetes
Category: Diseases and Conditions
Created: 1/31/2005 12:00:00 AM
Last Editorial Review: 9/8/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/NjkdaB

'Glycemic Index' May Be Too Unreliable to Manage Diabetes: Study

Title: 'Glycemic Index' May Be Too Unreliable to Manage Diabetes: Study
Category: Health News
Created: 9/7/2016 12:00:00 AM
Last Editorial Review: 9/8/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2ctJsx3

Intensive Type 2 Diabetes Treatment Can Extend Survival: Study

Title: Intensive Type 2 Diabetes Treatment Can Extend Survival: Study
Category: Health News
Created: 9/7/2016 12:00:00 AM
Last Editorial Review: 9/8/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2cHUJfc

Sugary Drink Warnings Hit Home With Teens

Title: Sugary Drink Warnings Hit Home With Teens
Category: Health News
Created: 9/8/2016 12:00:00 AM
Last Editorial Review: 9/8/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2bY2i1q

Health Tip: Protect Skin From Diabetes

Title: Health Tip: Protect Skin From Diabetes
Category: Health News
Created: 9/7/2016 12:00:00 AM
Last Editorial Review: 9/7/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2c8LtNc

Fried, Grilled or Baked Foods? They May Affect Type 2 Diabetes Risk

Title: Fried, Grilled or Baked Foods? They May Affect Type 2 Diabetes Risk
Category: Health News
Created: 9/2/2016 12:00:00 AM
Last Editorial Review: 9/2/2016 12:00:00 AM

Source MedicineNet Diabetes General http://ift.tt/2bKpEJb

Medical device-related pressure ulcers

Source Chronic Wound Care Management and Research http://ift.tt/2bHyWiN

Diabetes Advocacy With a Crown

“And the winner is . . .”

Nicole Johnson, Miss America 1999

You’ve just been crowned Miss America. Imagine hearing these words in front of thousands of people in the audience and millions watching at home. Now you will be on the road for more than 360 days out of the year supporting your platform. Your cause: Diabetes Education and Awareness.

While winning the title of Miss America can only happen to one person each year, many state titleholders promote their platform locally. But for those who do win the title of Miss America, it’s a once-in-a-lifetime experience. And it’s made even more special if the contestant has a close connection to diabetes—or even lives with it herself.

Nicole Johnson, PhD, was the first contestant with type 1 diabetes to win the Miss America competition in 1999. She was also the first to visibly wear her insulin pump on the runway.

“Becoming Miss America allowed me to have a voice and a platform that were immediately legitimate,” says Nicole. “At 24 it was incredible to go from college student to national advocate and spokesperson in a moment.”

The title of Miss America was a beginning, but certainly not an ending, for Nicole. Since she won the title, she has expanded her education and skills to help more people with diabetes than she ever could have imagined: “Today, I conduct diabetes behavioral research, run national programs and train others. Miss America was an incredible blessing—and something I continue to learn from even today.”

Nicole set the stage for many other contestants with a diabetes connection. In 2014, Sierra Sandison also chose to wear her insulin pump during the swimsuit portion of the Miss Idaho competition and won the state title. Her Facebook photo quickly went viral and inspired many young women to share their own pump photos with the #showmeyourpump hashtag.

Daja Dial, Miss South Carolina 2015, made it her mission to educate people about diabetes, in honor of her older brother. You can read more about her connection to diabetes via Diabetes Forecast magazine. Dial placed in the top 7 during last year’s event.

Age doesn’t limit your capacity to advocate. At the age of 17, Emily Brewer, Miss Arkansas’ Outstanding Teen 2016, has supported American Diabetes Association® events and advocacy programs at the local and state level. She recently won the Teens in Action award for her platform, Winning Against Diabetes, during the Miss America Outstanding Teen competition.

“I chose my platform because my uncle passed away at 23 due to complications with type 1 diabetes,” says Emily. “My great-aunt has type 2 diabetes, and both types are very common in my family. It’s something that I’ve seen firsthand and am very concerned and passionate about.”

Caroline Carter, Miss New Hampshire 2016

This year, Caroline Carter, Miss New Hampshire 2016, will compete on the national stage and attempt to follow Nicole Johnson’s footsteps. Carter was diagnosed with type 1 diabetes at the age of 12. She recently wore her insulin pump and continuous glucose monitor during the swimsuit portion of the Miss New Hampshire competition. “The diabetes community went wild,” Caroline says about winning her state’s title. “Ever since April, even to today, I have been getting pictures of children proudly showing their diabetes supplies.”

Caroline’s personal platform is “1, 2, We: Diabetes Advocacy.” During her year of service, she hopes to spread diabetes awareness and education, and break some of the stereotypes surrounding the disease.

“[Winning the Miss America title] would be such an amazing opportunity for me!” says Caroline. “I would have the ability to meet thousands of people with diabetes along my journey, and as Miss America, I would be able to educate not only my community, but also the nation on the dangers of this disease and ways to live with it.”

Whether you’re in front of a national audience or speaking locally with government officials, advocacy is an important part of the Association’s work. Thanks to advocates like Nicole Johnson and others across the country, we can transform the lives of all people with diabetes.

For more information on how to become a diabetes advocate, visit diabetes.org/advocate.

Source Diabetes Stops Here http://ift.tt/2bKJz4U